The Effects of Dexamethasone and Ibuprofen on Postoperative Analgesia in Patients Undergoing Hand and Forearm Surgery With Axillary Brachial Plexus Block

Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization79 enrolled

Overview

This study aims to comparatively examine the effects of preemptive IV dexamethasone and IV ibuprofen use on the duration of analgesia in ultrasound-guided ABPB (Axillary Brachial Plexus Block) applications for patients undergoing hand and forearm surgery. Furthermore, investigating the relationship between the study drugs and the incidence of PONV (Postoperative Nausea and Vomiting) and determining the time until the first use of rescue analgesic are also among the secondary objectives.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Axillary Block Dexamethasone Ibuprofen Hand Surgery Forearm Surgery Postoperative Analgesia

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient's consent to participate in the study (Informed consent) * Aged between 18 and 65 years * ASA physical status I or II * Being oriented and cooperative * Scheduled to undergo hand or forearm surgery * Body Mass Index (BMI) below 40 kg/m² * Scheduled for axillary brachial plexus blockade Exclusion Criteria: * Patient's refusal to participate in the study * Refusal of regional anesthesia * Known allergy to local anesthetics * Known allergy to ibuprofen * Known allergy to dexamethasone * Presence of coagulopathy * Local infection at the site of regional anesthesia application * Presence of malignancy at the surgical site * Diagnosis of diabetes mellitus * Body Mass Index (BMI) of 40 kg/m² or above * Duration of surgery exceeding 4 hours * Administration of opioid medication during the preoperative or intraoperative period

Outcomes

Primary Outcomes

Duration of analgesia

Duration of analgesia was defined as the time from the performance of the block until the patient's first report of pain.

Time frame: 24 hours

Secondary Outcomes

Incidence of PONV

The incidence of PONV during the first 24 hours following the block administration will be evaluated.