Effectiveness of Dexamethasone Injection for Reducing Pain After Third Molar Surgery

Overview

This randomized clinical trial aims to evaluate the effectiveness of dexamethasone injection in reducing postoperative pain after surgical removal of impacted mandibular third molars. Patients are divided into two groups: one receiving standard local anesthesia, and the other receiving an additional dexamethasone injection postoperatively. Pain levels are assessed using the Visual Analogue Scale (VAS) at 24, 48, and 72 hours after surgery. The study is conducted at 28 Military Dental Centre, Lahore.

Impacted mandibular third molar surgery is commonly associated with postoperative pain, which can affect patient comfort and recovery. Corticosteroids such as dexamethasone have anti-inflammatory properties and may reduce postoperative pain and swelling. This randomized clinical trial is designed to compare postoperative pain levels in patients undergoing third molar surgery with and without the administration of dexamethasone. Patients are randomly allocated into two groups. Group 1 receives standard inferior alveolar nerve block using 2% lignocaine with epinephrine. Group 2 receives an additional 1 ml (8 mg) dexamethasone injection in the buccal vestibule after completion of surgery. Pain is assessed using the Visual Analogue Scale (VAS) at 24, 48, and 72 hours postoperatively. All patients are prescribed the same postoperative analgesic regimen. The primary outcome is the difference in mean pain scores between the two groups. Data analysis is performed using SPSS, and statistical significance is set at p \< 0.05.

Conditions