Retrospective Single-center Analysis of Patients Presenting With Acute Neurological Symptoms, Aiming to Characterize the Frequency, Clinical Features, Diagnostic Pathways, and Healthcare Utilization of Patients with Functional Neurological Diseases
Study Type
OBSERVATIONAL
Enrollment
1,000
collection of patient data
University Hospital Basel
Basel, Switzerland
RECRUITINGFrequency of FND
The primary endpoint is the proportion of patients presenting with acute neurological symptoms who receive a diagnosis or likely differential diagnosis of Functional Neurological Disorder (FND) during their index hospital admission.
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Diagnostic Process Measures (%): Referral patterns and evaluation of alternative or concurrent neurological diagnoses.
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Diagnostic Resource Utilization (%): Clinical examination findings, neuroimaging, neurophysiological testing, and laboratory investigations.
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Healthcare Utilization and Outcomes (%): Discharge destination, readmission, outpatient follow-up, and in-hospital mortality.
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Quality of Care Associations (%) Demographic and clinical variables associated with diagnostic performance and healthcare utilization.
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Comparative Analyses: FND vs Non-FND (%): Differences in diagnostics, resource utilization, escalation of care, and short-term outcomes.
Time frame: At hospital discharge (index admission), up to 30 days from presentation
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Secondary Outcomes
Subtype Analyses (%): Differences across FND subtypes in presentation, diagnostics, management, and outcomes.
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Time to Definitive Diagnosis (days)
Time frame: At hospital discharge (index admission), up to 30 days from presentation
Secondary Outcomes
Length of Hospital Stay (days)
Time frame: At hospital discharge (index admission), up to 30 days from presentation