This is a cross-sectional, non-interventional qualitative study using individual interviews to investigate determinants of persistence with 3rd generation EGFR-TKI osimertinib as adjuvant therapy among patients with early-stage NSCLC in China. Approximately 100 participants will be enrolled, comprising around 85 patients and 15 physicians. All participants will be interviewed online or in-person using a COM-B (Capability, Opportunity, Motivation - Behaviour) based guide. Interviews will be conducted in waves, recorded, transcribed, and analysed using both deductive and inductive methods.
Study Type
OBSERVATIONAL
Enrollment
100
Research Site
Tianjin, China
Barriers to persistence
to identify factors that prevent patients from maintaining persistence to osimertinib adjuvant treatment. Barriers may include adverse effects, logistical challenges, financial constraints, psychosocial issues, communication gaps, etc.
Time frame: Day of interview completion
Facilitators of persistence
to determine factors that support patients in continuing osimertinib adjuvant treatment. Facilitators may include perceived efficacy, effective management of side effects, strong physician-patient communication, practical supports, family or peer encouragement, etc.
Time frame: Day of interview completion
Barriers and facilitators of persistence in different treatment duration cohorts
Barriers and facilitators of persistence in different treatment duration cohorts.
Time frame: Day of interview completion
Support needed by patients during their long-term treatment journey
Support needed by patients during their long-term treatment journey: to highlight what additional information, tools, or services patients feel would help sustain persistence
Time frame: Day of interview completion
AstraZeneca Clinical Study Information Center
CONTACT
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.