Assessment of Risk Factors for Acquiring Colonization With Candida Auris During an Outbreak in ICU.

Barzilai Medical Center771 enrolled

Overview

The study is aimed to assess the risk factors for acquiring candida auris skin colonization during an outbreak in an ICU.

Candida auris is unique when compared to other pathogenic fungi, as it spreads in the hospital rapidly. Therefore, it can cause healthcare-associated infections and outbreaks, it is resistant to antimicrobials and disinfectants and it is persisting on human skin and in the inanimate environment. There are few works listing factors found associated with candida auris candidemia, including longer CVC days, prior antibiotics, mechanical ventilation and longer ICU stay. Most of the research for candida auris risk factor doesn't differentiate colonization and infection, or, focuses on risk factors leading from colonization to infection. The study is aimed to assess the risk factors for acquiring candida auris skin colonization during an outbreak in an ICU.

Study Type

OBSERVATIONAL

Enrollment

771

Conditions

Candida Auris Colonization

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * hospitalization in ICU * Screened for candida auris Exclusion Criteria: * Age \<18 yeas. * No data. * No candida screen.

Locations (1)

Barzilai Medical Center

Ashkelon, Israel

Outcomes

Primary Outcomes

Colonization with Candida auris

Positive screening for candida auris, taken by nose/ armpits and groin swabs and either directly seeded on a selective medium or by positive PCR.

Time frame: From hospitalization in ICU until 2 weeks following discharge from ICU, a maximum of 90 days.

Data from ClinicalTrials.gov

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