Systemic Immun Inflamation Score Corelation in Postoperative Patients Prognosis

N/ANot Yet RecruitingNCT07544719

Malatya Egitim Ve Arastirma Hastanesi150 enrolled

Overview

The Systemic Immuno-Inflammation Index (SII) is a ratio derived from complete blood count parameters (neutrophils, lymphocytes, platelets) and is a non-invasive and easily calculable biomarker. The SIPI effectively reflects both local and systemic inflammatory responses in the human body. It has been used to predict and evaluate the prognosis of various solid tumors such as gastric cancer, non-small cell lung cancer, and colorectal cancer. Furthermore, the SIPI has been shown to have significant prognostic value in cardiovascular and cerebrovascular diseases. In this study, the SIPI will be calculated using laboratory data at the time of admission to the intensive care unit, and the relationship between the obtained values and the 30-day mortality status of the patients will be analyzed.

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Geriatric Anesthesia Postop Adult ICU Patients

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * The patient must be 65 years of age or older (in the geriatric age group), * Admitted to the intensive care unit after elective or emergency surgery * Have access to complete blood count (hemogram) data (neutrophils, lymphocytes, platelets) during their stay in the intensive care unit * Be able to undergo 30-day mortality monitoring from the date of admission to the intensive care unit * Have provided informed consent from the patient or their legal representative. Exclusion Criteria: * Patients under 65 years of age * Patients admitted to the intensive care unit for non-surgical reasons (e.g., trauma, medical intensive care indications) * Patients with deficient neutrophil, lymphocyte, or platelet counts upon admission to the intensive care unit * Patients with a history of malignancy, hematological disease, or immunosuppressive therapy * Terminally ill palliative patients * Patients who refuse informed consent.

Outcomes

Primary Outcomes

Measuring the Systemic Immune-Inflammation Index (SII) in postoperative patients to see the parameter's predictibility of 30-day mortality

In geriatric patients admitted to the intensive care unit after surgery, the Systemic Immune-Inflammation Index (SII) is a significant biomarker for predicting 30-day mortality.

Time frame: Postoperative day 1