The purpose of this study is to evaluate how well brenipatide (LY3537031) is tolerated what side effects may occur, and the safety and efficacy in participants with Irritable Bowel Syndrome-Constipation (IBS-C). The study drug will be administered subcutaneously (SC) (under the skin) when compared with placebo. The study will last approximately 35 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
342
Gastroenterology Health Partners Loc. 1
Louisville, Kentucky, United States
RECRUITINGPercentage of Participants with a Weekly Composite Clinical Response for at Least 50 Percent (%) of Weeks
Time frame: Week 9 to 16
Percentage of Participants with a Weekly Abdominal Pain Response for at Least 50% of Weeks
Time frame: Week 9 to 16
Percentage of Participants with a Weekly Complete Spontaneous Bowel Movement (CSBM) for at Least 50% of Weeks
Time frame: Week 9 to 16
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
CONTACT
Physicians interested in becoming principal investigators please contact
CONTACT
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