Subcision With Injection of Poly Deoxyribonucleotide Versus Subcision With Injection of Non-cross Linked Hyaluronic Acid in Rolling Acne Scars Treatment.

Patient and Observer Scar Assessment Scale (POSAS) - Observer Scale

Mean change in POSAS Observer Scale score from baseline.

Time frame: Baseline, Week 12, and Week 24 (3 months after last injection).

Patient and Observer Scar Assessment Scale (POSAS) - Patient Scale

Mean change in POSAS Patient Scale score from baseline.

Time frame: Baseline, Week 12, and Week 24 (3 months after last injection)

Proportion of patients with clinically significant POSAS improvement

Percentage of patients achieving \\ge30% improvement in total POSAS score.

Time frame: Week 12 and Week 24

Proportion of patients with \ge30% improvement in Goodman and Baron score

Percentage of subjects achieving \\ge30% improvement in the Goodman and Baron Quantitative Score.

Time frame: Week 12 and Week 24.

Change in total atrophic acne scar counts

Absolute change in total atrophic scar counts and Scar Global Assessment (SGA) using a 5-point scale (0 = clear to 4 = severe)

Time frame: Baseline, Week 12, and Week 24.

Success rate based on Scar Global Assessment (SGA)

Proportion of subjects achieving an SGA score of "clear" or "almost clear" and at least a 2-grade improvement from baseline.

Time frame: Week 12 and Week 24.

Patient Satisfaction Score

Proportion of patients achieving clinically meaningful improvement in satisfaction, defined as a \\ge2-point increase on a 10-point Visual Analog Scale (VAS).

Time frame: Week 12 and Week 24.

Absolute values of scar topography

Comparison of absolute values of acne scar area, volume, and maximum depth as assessed by Antera 3D imaging

Time frame: Baseline, Week 12, and Week 24.

Absolute values of Goodman and Baron Quantitative Score

Comparison of absolute values of the Goodman and Baron Quantitative Score for rolling acne scars.

Time frame: Baseline, Week 12, and Week 24