This study is a randomized controlled trial (RCT) with a pretest-posttest-follow-up design that compares the effectiveness of gamified teaching methods (Gimkit and educational escape room) with traditional theoretical education in improving undergraduate nursing students' Human Papillomavirus (HPV) knowledge and HPV literacy. Both HPV knowledge and HPV literacy were prespecified primary outcome measures in the study protocol. These outcomes represent related but distinct educational constructs and are reported separately to allow independent interpretation of each outcome.
This randomized controlled trial (RCT) with a pretest-posttest-follow-up design evaluated the effectiveness of two gamified teaching strategies in undergraduate nursing education. The study was conducted among third-year nursing students enrolled in the Obstetrics and Gynecology Nursing course at Aydın Adnan Menderes University. Participants were randomly assigned to one of three groups: 1. Gimkit-based gamification combined with theoretical education 2. Educational escape room combined with theoretical education 3. Control group (theoretical education only) All participants received standardized theoretical instruction on Human Papillomavirus (HPV). Subsequently, participants in the intervention groups completed either the Gimkit or educational escape room activity, whereas the control group received no additional educational intervention. Data were collected using the following instruments: * Student Information Form * Human Papillomavirus (HPV) Knowledge Scale * Human Papillomavirus Literacy Scale (HPV-LS) * Gameful Experience Scale (GAMEX) Both HPV knowledge and HPV literacy were prespecified primary outcome measures in the study protocol. HPV knowledge and HPV literacy address related but distinct educational constructs and are reported separately to allow independent interpretation of each outcome. Data were analyzed using IBM SPSS Statistics version 25.0. Descriptive statistics were calculated for all variables. Baseline continuous variables were compared using one-way analysis of variance (ANOVA), whereas categorical variables were analyzed using the chi-square test or Fisher's exact test, as appropriate. Changes in study outcomes over time were evaluated using two-way repeated-measures ANOVA with Bonferroni-adjusted pairwise comparisons, as appropriate. Statistical significance was set at p \< 0.05.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
90
Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in a Gimkit-based digital quiz game consisting of multiple-choice and true/false questions designed to reinforce HPV-related knowledge.
Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in structured escape room-based learning activities consisting of crossword puzzles, word search tasks, and matching exercises designed to reinforce HPV-related knowledge.
Aydın Adnan Menderes University
Aydin, Turkey (Türkiye)
HPV Knowledge Level
Human Papillomavirus (HPV) Knowledge Scale. Scores range from 0 to 33; higher scores indicate greater knowledge.
Time frame: Baseline (Day 0, before theoretical education; 17 April 2026), immediately after theoretical education (Day 0; 17 April 2026), immediately after the intervention (Day 7; 24 April 2026), and follow-up (Day 28; 15 May 2026).
HPV Literacy Level
Human Papillomavirus (HPV) Literacy Scale. Scores range from 24 to 120; higher scores indicate higher literacy.
Time frame: Baseline (Day 0, before theoretical education; 17 April 2026), immediately after theoretical education (Day 0; 17 April 2026), immediately after the intervention (Day 7; 24 April 2026), and follow-up (Day 28; 15 May 2026).
Gamified Learning Experience
Measured using the Gameful Experience Scale (GAMEX). Higher scores indicate a more positive gamified learning experience.
Time frame: Immediately after completion of the gamified intervention (Day 7; 24 April 2026).
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