Evaluate the efficiency of audiovisual stimulation in virtual reality for improving the visual perception of children, adolescents, and young adults with hemianopia resulting from pediatric brain tumors. These individuals can lose up to 50% of their visual field, significantly impacting their independence, mobility, and daily lives.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
120
Our audiovisual stimulation procedure IVR, called 3D-MOT, was encoded using the the 3D Unity programming platform and deployed in HMDs with built-in head/eye tracking. We implemented the multiple object tracking (MOT) paradigm, developed in the 80's to study visual attention in humans, and added correlated spatial sound.
During this phase, the patients will be at home without a headset and will not be exposed to an audio-visual stimulation task in virtual reality.
Department of Paediatric and adolescents medicine, Medical University
Vienna, Austria
Paediatrics and Adolescents Medicine, University Hospital
Copenhagen, Denmark
Hôpital de Hautepierre
Strasbourg, France
Institute of Tumour, department of haematology and Oncohaematology paediatric
Milan, Italy
Paediatric Haematology, University Hospital
Padova, Italy
Princess Maxima Centre for Paediatric Oncology
Utrecht, Netherlands
Paediatric Oncology, San Joan de Deu
Barcelona, Spain
Great Ormond Street Hospital for Children
London, United Kingdom
Visual field perimetry measured using the Esterman binocular field test
Increase at least 3 points in the number of points perceived in the blind field at the Esterman binocular field test after intervention (8 weeks) when compared to baseline and between control and interventional group.
Time frame: From enrollment to the end of follow up period at 6 months
Participant-reported a vision impairment specific quality of life questionnaire: Impact of Vision Impairment Questionnaire (IVI).
Questionnaire will be provided and compared at baseline and after intervention ( 8 weeks) and between control and interventional group. A diminution of the mean score above 0.3-0.5 point will be consider as an amelioration of quality of life impacted by vision impairment.
Time frame: From enrollment to the end of follow up period at 6 months
Reading speed - Minnesota Low Vision Reading (MNREAD) test
Reading speed will be assessed and compared at baseline and after intervention (8 weeks) and between control and interventional groups. An increase in reading speed of 8.6 words per minute on the Minnesota Low Vision Reading (MNREAD) test will be considered an improvement in the variable.
Time frame: From enrollment to the end of follow up period at 6 months
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