The goal of this study is to learn if an online computerized training program improves processing speed, attention, and working memory in children with a primary brain tumor during and after active cancer treatment. The main questions it aims to answer are: 1. Is the cognitive intervention feasible to administer to children with brain tumors during and after cancer treatment?, 2. Is the cognitive intervention acceptable to children and caregivers?, and 3. Does the cognitive intervention improve neuropsychological functioning? There is no comparison group for this study. Participants will: 1. Complete an online computerized cognitive training program for approximately 15 minutes per day, 5 days a week, for 8 weeks; 2. Have weekly check-ins with the cognitive coach, 3. Complete a survey at the end of the cognitive training program, and 4. Complete pre- and post- neuropsychological testing.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
300
This online cognitive training program aims to improve processing speed through computerized cognitive exercises. Participants will complete approximately 15 minutes of training, 5 days per week for 8 weeks. Weekly check-ins with a cognitive coach will assist with engagement and problem solve any barriers.
Kennedy Krieger Institute
Baltimore, Maryland, United States
Feasibility - Enrollment
Study enrollment rate.
Time frame: Up to 5 years after diagnosis.
Feasibility - Participant Retention
Number of participants who complete the computerized brain training program.
Time frame: 8 weeks
Feasibility - Intervention Adherence
Number of levels completed in the cognitive training program. Qualitative feedback regarding barriers and facilitators to engagement will also we collected to provide descriptive context.
Time frame: Through study completion, an average of 8 weeks.
Feasibility - Total Intervention Time
Total time spent completing the cognitive training program exercises.
Time frame: 8 weeks
Acceptability
Parent and self-reported acceptability measured using a Likert-scale questionnaire administered at the end of the intervention. Mean total score will be reported. Qualitative feedback regarding participant experience will also be collected to provide descriptive context.
Time frame: At the end of the 8-week intervention.
Cognitive Training Task-Based Performance
Changes in neuropsychological functioning, as measured by the train-to-task activity.
Time frame: Prior to the intervention, immediately following intervention, and 6 months after intervention completion.
Processing Speed
Changes in processing speed as measured by the NIH toolbox.
Time frame: Prior to the intervention, immediately following intervention, and 6 months after intervention completion.
Attention
Changes in attention as measured by the NIH toolbox.
Time frame: Prior to the intervention, immediately following intervention, and 6 months after intervention completion.
Working Memory
Changes in working memory as measured by the NIH toolbox.
Time frame: Prior to the intervention, immediately following intervention, and 6 months after intervention completion.
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