Efficacy of Selective COX-2 Inhibitors in Relieving Orthodontic Pain

Phase 1Active Not RecruitingNCT07559682

Sharif Medical Research Center150 enrolled

Overview

The purpose of this study is to compare the efficacy of selective COX-2 inhibitors{ etoricoxib vs celecoxib )in relieving orthodontic pain , after initial bonding and arch wire insertion.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Enrollment

150

Conditions

Orthodontic Pain (D013850)

Interventions

CelecoxibDRUG

Group A will be given Celecoxib 50mg once a day.

Etoricoxib (Treatment Group)DRUG

Group B will be given Etoricoxib 60mg once a day.

Eligibility

Sex: ALLMin age: 13 YearsMax age: 30 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Age 13 to 30 years 2. Fully erupted permanent dentition excluding third molars 3. Mild crowding (0 -4mm) Exclusion Criteria: 1. Active periodontitis 2. Deep cavities or large restorations 3. Previous dental extraction in less than 4 weeks before bonding 4. History of steroid use within last 6 weeks

Locations (1)

Sharif Medical City Lahore

Lahore, Pakistan

Outcomes

Primary Outcomes

Pain intensity

Pain scores will be measured using a 10cm Visual Analogue Scale (VAS) , The Scale consists of a horizontal line anchored by two verbal descriptions where 0 represented '' No Pain '' and 10 represented ''Maximum Pain''. The Score is determined by measuring the distance from left end of the scale to the mark made by the participant.

Time frame: 1 year

Data from ClinicalTrials.gov

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