Patients with stable vitiligo with 2 or more symmetric patches, 2 on acral sites and/or 2 on non acral sites will be recruited and assessed for eligibility for inclusion to receive NB-UVB on the whole body, and carboxytherapy on one randomized side.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
59
Narrow-Band Ultraviolet B phototherapy full cabin
Narrow-Band Ultraviolet B phototherapy full cabin combined with Intradermal injection of carbon dioxide gas
Faculty of Medicine, Cairo University
Cairo, El Manial, Egypt
Vitiligo Extent Score for a Target Area (VESTA)
Assessment of the treatment response in a target area Range 0-100%
Time frame: 6 months- 1 year
Estimation of human E-Cadherin using ELISA
Time frame: 6 months -1 year
Estimation of malondialdehyde by spectrophotometer
Time frame: 6 months-1 year
Patients' global satisfaction
five-point grading scale -1-3
Time frame: 6 months -1 year
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