Local literature is deprived of data comparing the effectiveness of esomeprazole and vonoprazan in patients with gastroesophageal reflux disease (GERD). This study was planned with the objective of comparing the effectiveness of esomeprazole versus vonoprazan in patients diagnosed with GERD.
Addressing the pressing need for an in-depth understanding and comparison of treatment options for the escalating prevalence of GERD, a condition significantly impacting patients' quality of life, is crucial. The study's results would not only provide local data, but also help doctors choose between esomeprazole and vonoprazan as the best treatment option. This would improve patient care and help doctors make better decisions, which would ultimately lead to better management of GERD and the overall health of patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
824
Patients received a once-daily dose of 20 mg of esomeprazole after the evening meal for 4 weeks.
Patients received a once-daily dose of 20 mg of vonoprazan after the evening meal for 4 weeks.
Allama Iqbal teaching hospital
Dera Ghazi Khan, Punjab Province, Pakistan
Sufficient relief
The frequency of patients who achieved sufficient relief was noted.
Time frame: 4 weeks
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