Skin Hydration and Facial Aging in Women Aged 30-60: An Observational Correlational Study Using Bioimpedance Analysis

IAS Skin Care30 enrolled

Overview

This study investigates whether skin hydration levels are related to how old the skin looks. Thirty women aged 30 to 60 years will attend a single visit at a licensed esthetic practice in Florida. Skin moisture will be measured at seven points on the face using the BT-Analyze device. Photographs will be taken and evaluated by a blinded expert cosmetologist using a standard aging scoring system. The study will determine whether women with lower skin hydration tend to show more visible signs of aging.

Skin hydration is maintained through hyaluronic acid, natural moisturizing factor (NMF), and the lipid barrier of the stratum corneum. Dehydration activates matrix metalloproteinases (MMPs) which degrade collagen and elastin, accelerating visible aging. This cross-sectional observational study will enroll 30 women in three age groups (30-40, 40-50, and 50-60 years). Hydration will be assessed using BT-Analyze across seven facial zones. The primary outcome is the Spearman rank correlation between mean hydration score and modified Glogau visual aging score (0-18 points). Covariates include age, Fitzpatrick skin type, daily water intake, menopausal status, and skincare habits.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Skin Aging Skin Hydration Facial Aging Transepidermal Water Loss

Eligibility

Sex: FEMALEMin age: 30 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Female, aged 30 to 60 years Willing to attend one study visit without makeup No cosmetics applied for at least 4 hours prior to the visit Able to acclimate in controlled indoor environment for 20 minutes Signed written informed consent Exclusion Criteria: Active dermatological conditions (eczema, psoriasis, rosacea in flare) Injectable cosmetic procedures within the past 6 months Systemic medications affecting skin condition (oral retinoids, systemic corticosteroids) Pregnancy or lactation Uncontrolled systemic conditions known to significantly affect skin (e.g., uncontrolled diabetes mellitus)

Outcomes

Primary Outcomes

Spearman Correlation Between BT-Analyze Mean Score and Modified Glogau Visual Aging Score

Spearman rank correlation coefficient (rs) between mean BT-Analyze hydration score (mean of seven facial zones, 0-65 units) and total modified Glogau visual aging score (0-18 points) assessed by a blinded expert cosmetologist.

Time frame: At single study visit (Day 1)

Secondary Outcomes

BT-Analyze Score Comparison Across Age Groups

Kruskal-Wallis comparison of mean BT-Analyze hydration scores between three age groups (30-40, 40-50, 50-60 years).