The goal of this trial is to learn if Pregabalin is better than Acetaminophen in pain management of patients with Post-Mastectomy pain Syndrome, which is defined as pain in the scar, chest wall, shoulder after undergoing mastectomy or breast-conservation (BCS). It could be burning, stabbing, shooting pain or pins-and-needle sensation. Participants will: * Take their prescribed allotted medicine for 14 days. * Will visit the clinic at 2 and 6 week interval for assessment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
158
1 tablet of 75 mg taken orally, once daily at night for 14 days, without interruption.
2 tablets of 500mg, taken orally, three times a day, 8 hours apart, for 14 days, without interruption.
Sindh Institute of urology and Transplantation
Karachi, Pakistan
Change from Baseline in the Visual Analogue Score at 2 weeks
Zero is equivalent to no pain, and 10 indicates the worst possible pain.
Time frame: Baseline and 2 weeks
Change from Baseline in the Visual Analogue Score at 6 weeks
Zero is equivalent to no pain, and 10 indicates the worst possible pain.
Time frame: Baseline and 6 weeks
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