To compare suzetrigine versus hydrocodone/acetaminophen for postoperative pain control following dermatologic surgery.
This study is a randomized, controlled trial that is evaluating the safety and efficacy of suzetrigine as a postoperative pain medication compared to the standard of care Hydrocodone/Acetaminophen in patients undergoing Mohs micrographic surgery (MMS) who are at high-risk for postoperative pain and opioid use. The goal is to reduce opioid prescription use and give patients a non-opioid pain medication option for particularly painful surgeries. Patients will be randomized into one of two groups, one group will receive the interventional medication and the other the standard of care medication.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
75
Standard of care drug
Control Drug
Baylor University Medical Center
Dallas, Texas, United States
Change in need for opioid medication for pain management after Mohs micrographic surgery
Change in mean visual analog scale (VAS; 0-10) pain scores at 24 and 48 hours after surgery with a minimal change in pain score of 1.0 points.
Time frame: 48hours post surgery
Patient-reported adequacy of pain control
Assessment of pain control with use of medication following surgery.
Time frame: 48hours post surgery
Rescue pain management use
Changes in need to use rescue medication for pain management
Time frame: 48hours post surgery
Adverse Events
Evaluation of occurence of adverse events (irregular heart beat, abnormal blood pressure, change in consciousness, or need for urgent care or emergency room visit in the first 3 days after surgery).
Time frame: 3 days after surgery
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