A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)

Percent change from baseline in body weight

Time frame: Baseline (Week 0) to Week 60

Change from baseline in body weight

Time frame: Baseline (Week 0) to Week 48 and Week 60

Percentage of participants who achieve ≥5% of body weight reduction from baseline

Time frame: Baseline (Week 0) to Week 48 and Week 60

Percentage of participants who achieve ≥10% of body weight reduction from baseline

Time frame: Baseline (Week 0) to Week 48 and Week 60

Percentage of participants who achieve ≥15% of body weight reduction from baseline

Time frame: Baseline (Week 0) to Week 48 and Week 60

Percentage of participants who achieve ≥20% of body weight reduction from baseline

Time frame: Baseline (Week 0) to Week 48 and Week 60

Percentage of participants who achieve ≥25% of body weight reduction from baseline

Time frame: Baseline (Week 0) to Week 48 and Week 60

Number of participants with treatment emergent adverse events (TEAEs) and serious adverse events (SAEs)

Time frame: Up to Week 70