Studying Heart Ablation After Left Atrial Closure in High-Bleeding-Risk Atrial Fibrillation Patients

University of Chicago198 enrolled

Overview

The purpose of this multicenter study is to collect information from routine clinical practices for patients with left atrial appendage occlusion (LAAO) devices presenting for pulmonary vein isolation (PVI) or left atrial ablation. Assessment will include characterization of patient characteristics, procedural details, management of post-procedure anticoagulation, and clinical outcomes.

Study Type

OBSERVATIONAL

Enrollment

198

Conditions

Atrial Fibrillation Atrial Arrhythmia

Interventions

Data collectionOTHER

Data collection on patient characteristics and comorbidities, baseline echocardiographic data, home medications including oral anticoagulation regimen, ablation data, left atrial appendage occlusion device data, and complication-related details from routine procedures and encounters

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Individuals aged \>18 years * Undergoing any type of atrial fibrillation ablation or left atrial arrhythmia ablation Exclusion Criteria: * Missing essential baseline characteristics and/or missing collection of sufficient details regarding each complication

Locations (20)

Rush University Medical Center

Chicago, Illinois, United States

University of Chicago

Chicago, Illinois, United States

Outcomes

Primary Outcomes

Patient characteristics

Data will be collected to characterize patients with left atrial appendage occlusion devices presenting for pulmonary vein isolation or left atrial ablation

Time frame: Month 0, baseline

Procedural characteristics

Data will be collected to characterize pulmonary vein isolation or left atrial ablation procedural details for patients with left atrial appendage occlusion devices

Time frame: Month 0, during procedure

Post-procedure anticoagulation management

Data will be collected to characterize post-procedure anticoagulation management for patients with left atrial appendage occlusion devices

Time frame: Through 24 months

Clinical outcomes

Data will be collected to characterize clinical outcomes for patients with left atrial appendage occlusion devices presenting for pulmonary vein isolation or left atrial ablation

Time frame: Through 24 months

Secondary Outcomes

Procedure-related complications

Data will be collected to characterize procedure-related complications for patients with left atrial appendage occlusion devices presenting for pulmonary vein isolation or left atrial ablation

Time frame: Through 6 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.