split-mouth RCT. 12 patients. horizontal GBR performed. 2 grafts were compared: test was LPRF block, control was 50% autogenous bone and 50% DBBM. 25 months follow-up.
12 patients were included in this split-mouth RCT. In test sites a horizontal GBR procedure was performed using a collagen membrane with a graft consisting of 50% autogenous bone and 50% DBBM. In control sites a collagen membrane was used, with a graft consisting of an LPRF block. This was left to heal for 9 months. Subsequently an implant was placed. At time of implant placement a bone biopsy was taken. After 4 months of osseointegration the abutment connection was performed. 1 year after loading of the implants a final check was done. CBCT scans were taken at intake, immediately after reconstruction, 9 months after reconstruction, before implant placement and 1 year after loading of the implants. Primary outcome measure is the bone volume as measured on the CBCT scans. Secondary outcome measures are bone quality in the biopsy, buccal bone thickness around the oral implant, number and type of complications, cumulative survival rates of the implants 1 year after loading.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
12
Bone grafting procedure using a particulated bone graft, covered by a resorbable membrane
UZ Leuven
Leuven, Vlaams-Brabant, Belgium
bone volume changes
bone volume is measured on CBCT scans of the jaw
Time frame: at intake, immediately after surgery, 9 months postoperative, 13 months postoperative, 25 months postoperative
buccal bone thickness on CBCT scan
thickness of the buccal bone plate of the oral implant
Time frame: measured at placement of the implant and 1 year later
Cumulative survival rate of the implants
survival of the implants over the follow-up time
Time frame: measured at the 1 year loading follow-up
Rates of complications
all possible complications were registered and monitored
Time frame: from the gbr surgery to 25 months follow-up
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