Evaluation of Slit-like Adjusted Mathieu Versus Onlay Island Flap for Hypospadias Repair in Pediatrics

N/ACompletedNCT07592026

Al-Azhar University80 enrolled

Overview

* Purpose\*\* To compare the Slit-like Adjusted Mathieu (SLAM) technique versus the inner transverse preputial onlay island flap for repair of anterior and mid-penile hypospadias with narrow urethral plate, evaluating complication rates, surgical outcomes, and cosmetic results. * Methods\*\* This prospective randomized controlled study included 80 patients with anterior and mid-penile hypospadias with a urethral plate \<6 mm, conducted at Al-Azhar University Hospitals, Cairo, Egypt, from May 2020 to October 2025. Patients were randomly allocated to SLAM repair (Group A, n=40) or inner transverse preputial onlay island flap (Group B, n=40). Follow-up ranged from 24 to 48 months. Outcomes were assessed using the Hypospadias Objective Scoring Evaluation (HOSE) questionnaire.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Narrow Urethral Plate Hypospadias

Interventions

Eligibility

Sex: MALEMin age: 6 MonthsMax age: 12 Years

Medical Language ↔ Plain English

Inclusion Criteria: * anterior or mid-penile hypospadias * shallow and narrow urethral plate measuring \<6 mm, * without or with mild penile curvature \<30° after degloving Exclusion Criteria: * wide urethral plate suitable for Tubularized Incised Plate (TIP) urethroplasty, * other types of hypospadias (penoscrotal, scrotal, or perineal), * moderate or severe penile curvature (\>30°) * recurrent cases

Outcomes

Primary Outcomes

postoperative complications

Time frame: Follow-up was performed at 1, 3, 12, and 24 months to assess complications

Secondary Outcomes

Hypospadias Objective Scoring Evaluation score

a validated 5-point system, ranging from 5 to 16

Time frame: at 12 months