The main aim of this study is to compare the effects of two different anesthesia methods-(1) general anesthesia alone and (2) combination of general anesthesia with cervical plexus block-on postoperative inflammatory process and amino acid metabolism in patients undergoing thyroidectomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
In our study, one patient group will receive only general anesthesia, while the other group will receive general anesthesia in addition to ultrasound-guided cervical plexus block. The inflammatory response is a natural response of the body's immune system to surgical trauma, and it can vary depending on the anesthetic agent used. In regulating this response, molecules such as IL-1β, TNF-α, IL-6, IL-10, and IL-40 are important indicators that determine the severity and duration of inflammation. These parameters will be examined and compared in both groups.
In our study, one patient group will receive only general anesthesia, while the other group will receive general anesthesia in addition to ultrasound-guided cervical plexus block.
Perioperative Inflammatory Response
IL-1β, TNF-α, IL-6, IL-10, and IL-40 levels will be measured 1 hour before surgery, and then 2 and 6 hours after surgery, and these values will then be compared.
Time frame: Before the procedure, and at 2 and 6 hours after the procedure.
Inflammatory Response
IL-1β, TNF-α, IL-6, IL-10, and IL-40 levels will be measured 1 hour before surgery, and then 2 and 6 hours after surgery, and these values will then be compared.
Time frame: Before the procedure, and at 2 and 6 hours after the procedure.
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