Healthcare-associated infections (HAIs) remain a major cause of morbidity, mortality, and healthcare costs worldwide. Hand hygiene is the cornerstone of infection prevention; however, adherence to the full WHO 6-step hand hygiene technique may be limited in routine clinical practice due to time constraints and workflow barriers. Simplified hand hygiene approaches may improve compliance while preserving clinical effectiveness. The Easy Hands study is a pragmatic cluster randomized cross-over trial designed to compare a simplified 3-step hand hygiene technique with the standard WHO 6-step technique in clinical care units. Hospital services were randomized to one of two sequences of intervention and crossed over after the first study period. The primary objective is to evaluate whether the simplified 3-step technique is associated with differences in time to first healthcare-associated infection among hospitalized patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
1,027
Simplified 3-step hand hygiene protocol implemented in assigned clusters during the intervention period.
Standard WHO 6-step hand hygiene protocol implemented in assigned clusters during the comparator period.
Fundación Clínica Shaio
Bogotá, Bogota D.C., Colombia
Time to First Healthcare-Associated Infection
Time from hospital admission to first documented healthcare-associated infection according to institutional surveillance criteria.
Time frame: During hospitalization, up to 30 days
Incidence Density of Healthcare-Associated Infections
Cases per 1,000 patient-days.
Time frame: During hospitalization, up to 30 days
Cumulative Incidence of Healthcare-Associated Infections
Proportion of patients developing at least one HAI during follow-up.
Time frame: During hospitalization, up to 30 days
Hand Hygiene Compliance
Percentage adherence to the assigned hand hygiene technique measured through direct observational audits using institutional hand hygiene monitoring procedures.
Time frame: During hospitalization, up to 30 days
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