Recent advances in breast surgery, together with the increasing adoption of conservative surgical approaches, have renewed interest in pre-pectoral implant-based breast reconstruction. Within this reconstructive paradigm, surgeons may employ two distinct strategies: (i) immediate reconstruction using a direct-to-implant approach (DTI), or (ii) a two-stage reconstruction consisting of tissue expander placement followed by definitive implant insertion (TE-I). Each approach is associated with specific indications, advantages, and inherent limitations. The EXPRESSO study aims to retrospectively compare surgical outcomes between pre-pectoral DTI and TE-I breast reconstruction. By providing real-world evidence on these reconstructive strategies, this study seeks to inform surgical decision-making and to optimize reconstructive outcomes in contemporary breast cancer care.
Study Type
OBSERVATIONAL
Enrollment
276
Primary objective
To evaluate the rate of implant loss within 3 months per patient
Time frame: 3 months post-surgery
Secondary objectives
To evalueate early and late-onset postoperative complications and to revaluate re-admission and re-operation rates
Time frame: 3, 12, 24 months post-surgery
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