Obstructive sleep apnea is a common disorder associated with significant cardiovascular and metabolic risks. Polysomnography is considered the gold standard for diagnosis and severity assessment; however, it may not fully reflect symptom burden and comorbidity profiles. The Baveno classification has been proposed as a multidimensional clinical tool that integrates symptoms and comorbidities to guide treatment decisions. This retrospective study aims to evaluate the agreement between the Baveno classification and polysomnography results in patients with obstructive sleep apnea. The study includes adult patients who underwent overnight polysomnography between January 2016 and June 2024. Clinical data, including symptom burden and comorbid conditions, were collected from medical records and used to classify patients according to the Baveno system. The primary objective is to assess the concordance between the Baveno classification and polysomnography-based disease severity and treatment recommendations. Secondary analyses explore the distribution of disease severity across Baveno groups and the potential implications for clinical decision-making. The findings of this study may provide insight into the clinical utility of the Baveno classification as a complementary tool to polysomnography in the management of obstructive sleep apnea.
Obstructive sleep apnea is a heterogeneous disorder characterized not only by the frequency of respiratory events during sleep but also by variable symptom burden and associated comorbidities. While polysomnography remains the reference standard for diagnosis and severity classification, reliance on respiratory event indices alone may not fully capture the clinical complexity of the disease. The Baveno classification has been proposed as a multidimensional approach that incorporates symptom burden and comorbidity status to support individualized management strategies. This retrospective observational study evaluates the relationship between the Baveno classification and polysomnography-based findings in patients with obstructive sleep apnea. The study population consists of adult patients who underwent overnight polysomnography in a tertiary care sleep laboratory between January 2016 and June 2024. Demographic, clinical, and sleep study data were retrieved from institutional electronic medical records and sleep laboratory archives. Patients were categorized according to polysomnography-based disease severity using the apnea-hypopnea index and separately classified into Baveno groups based on symptom burden and the presence of comorbid conditions. The analysis focuses on the level of agreement between these two classification approaches and their implications for treatment decision-making. In particular, concordance in treatment recommendations derived from each classification framework is examined. By comparing a physiology-based diagnostic standard with a clinically oriented classification system, this study aims to provide further evidence regarding the applicability of multidimensional assessment strategies in the management of obstructive sleep apnea.
Study Type
OBSERVATIONAL
Enrollment
395
Concordance between PSG-based and Baveno-based PAP treatment indication
Description: Agreement between PSG-defined PAP indication (AHI ≥15 events/hour) and Baveno-based PAP indication (Groups B/C/D vs Group A). Measurement Tool: Cohen's kappa coefficient (κ) Unit of Measure: Kappa value (κ)
Time frame: Time Frame: Baseline sleep study assessment
Apnea-Hypopnea Index (AHI)
Description: OSA severity assessed by overnight polysomnography. Measurement Tool: Full-night PSG Unit of Measure: Events/hour
Time frame: Time Frame: Baseline sleep study assessment
Epworth Sleepiness Scale (ESS) score
Description: Daytime sleepiness assessed using ESS questionnaire. Scale Range: 0-24; higher scores indicate greater sleepiness. Unit of Measure: ESS score
Time frame: Time Frame: Baseline clinical evaluation
Oxygen Desaturation Index (ODI)
Description: Frequency of oxygen desaturation events measured during overnight polysomnography. Measurement Tool: Full-night PSG Unit of Measure: Events/hour
Time frame: Time Frame: Baseline sleep study assessment
Minimum Oxygen Saturation (Minimum SpO₂)
Description: Lowest oxygen saturation level recorded during overnight polysomnography. Measurement Tool: Pulse oximetry during PSG Unit of Measure: Percentage (%)
Time frame: Time Frame: Baseline sleep study assessment
Reclassification rate of PAP indication
Measure Description: Proportion of patients whose PAP treatment recommendation differed between PSG-based classification and Baveno classification. Measurement Tool: Cross-classification analysis Unit of Measure: Percentage (%)
Time frame: Baseline sleep study assessment
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