Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder

Prisma Health-Upstate70 enrolled

Overview

This study examines the effects of e-cigarette (EC) flavors among adults with opioid use disorder (OUD) receiving buprenorphine treatment who currently use e-cigarettes. Participants will smell and rate 11 EC flavors based on appeal, sensory characteristics, and likelihood of future use. Researchers will examine how different flavor profiles influence the appeal and reinforcing effects of ECs in this population. The goal is to identify EC flavors that may enhance the acceptability of ECs as a potential harm-reduction strategy among adults with OUD receiving buprenorphine treatment.

This study examines the effects of e-cigarette (EC) flavors among adults with opioid use disorder (OUD) who are receiving buprenorphine treatment and currently use e-cigarettes. Participants will complete a brief session in which they will smell and rate 11 EC flavors based on their appeal, sensory characteristics, and likelihood of future use. Researchers will examine how different flavor profiles influence the appeal, positive subjective effects, and reinforcing potential of EC flavors in this population. The goal of the study is to identify one or more EC flavors that may enhance the acceptability and reinforcing effects of ECs as a potential harm-reduction strategy among adults with OUD receiving buprenorphine treatment.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Nicotine Use Disoder Opioid Use Disorder

Interventions

Eligibility

Sex: ALLMin age: 21 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adults aged 21 years or older. * Current e-cigarette users who report e-cigarette use on ≥20 of the past 30 days. * Former daily cigarette smokers who currently smoke on ≤19 days per month and no more than 5 cigarettes per day. * Diagnosed with opioid use disorder (OUD). * Currently receiving buprenorphine treatment for OUD. Exclusion Criteria: \-

Outcomes

Primary Outcomes

Perceived Sweetness

Perceived sweetness of each e-cigarette flavor will be assessed using a one-item VAS ranging from "Not sweet at all" to "Extremely sweet," with higher scores indicating greater perceived sweetness.

Time frame: Baseline session

Perceived Coolness/Freshness

Perceived coolness/freshness of each e-cigarette flavor will be assessed using a one-item VAS ranging from "Not cool/fresh at all" to "Extremely cool/fresh," with higher scores indicating greater perceived coolness/freshness.

Time frame: Baseline session

Perceived Flavor Strength

Perceived flavor strength will be assessed using a one-item VAS ranging from "Very weak" to "Very strong," with higher scores indicating greater perceived flavor strength.

Time frame: Baseline session

Perceived Harshness/Irritation

Perceived harshness/irritation of each e-cigarette flavor will be assessed using a one-item VAS ranging from "Not harsh/irritating at all" to "Extremely harsh/irritating," with higher scores indicating greater perceived harshness/irritation.

Time frame: Baseline session

Flavor Liking

Flavor liking will be assessed using a one-item VAS ranging from "Not at all" to "Extremely," with higher scores indicating greater liking of the flavor.

Time frame: Baseline session

Likelihood of Future Use

Likelihood of future use will be assessed using a one-item VAS ranging from "Not at all" to "Definitely," with higher scores indicating greater likelihood of future use of the flavor.

Time frame: Baseline session

Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Central Contacts