Children With Autism and Social Interaction Processing

University of Electronic Science and Technology of China59 enrolled

Overview

Attention allocation in ASD vs. TD children viewing social/non-social interactions by adult/child models, and the dynamics of social attention.

Participants: ASD group: 30 children; TD group: 29 children; age- and sex-matched. Apparatus: Non-invasive eye tracker (Tobii Pro Spectrum). Stimuli: Eight 60-second videos (4 with child models, 4 with adult models). Questionnaires/Assessments: SRS, AQ, SCQ, ADOS-2, PPVT. Experimental design: A 2 (group: TD, ASD) × 2 (model type: adult, child) × 2 (context: interactive, non-interactive) × 2 (phase: baseline, test) mixed design. Task: Free viewing of eight videos presented in random order.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Autism Spectrum Disorder (ASD)

Eligibility

Sex: ALLMin age: 3 YearsMax age: 9 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \- For ASD group: confirmed clinical diagnosis of Autism Spectrum Disorder(DSM-5/ADOS-2) For TD group：TD children without any developmental or neurological disorders Both groups：Normal or corrected-to-normal vision，no color vision deficiencies，and legal guardian provided written informed consent Exclusion Criteria: \- TD group: meet the study's group-specific screening cutoffs on SRS, SCQ or AQ ASD group：Failure to meet the study's group-specific screening cutoffs on ADOS-2 Both groups：Known genetic syndromes，significant hearing loss or uncorrectable visual impairment

Locations (1)

School of Foreign Languages, University of Electronic Science and Technology of China

Chengdu, Sichuan, China

Outcomes

Primary Outcomes

Proportion of total fixation duration on human faces, context, activity areas

Proportion of total fiaxtion duration on human faces, context, activity areas was calculated as (total fixation duration on AOIs/ total fixation duration on the screen).

Time frame: During the full 8 minutes video presentation

Number of saccades on human faces, context, activity areas

The number of saccades on human faces, context, activity areas occurring during an interval.

Time frame: During the full 8 minutes video presentation

Social Prioritization Score on human faces, context, activity areas

The difference in the proportion of fixation time between social and non-social interaction information.

Time frame: During the full 8 minutes video presentation

Data from ClinicalTrials.gov

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