The design is a prospective, observational registry for subjects with CHE under the care of dermatology or other qualified healthcare provider. Longitudinal data are collected from both subjects and their treating provider during routine clinical encounters using a structured and standardized data collection method
The objective of the registry is to create a cohort of CHE subjects to evaluate long-term real world safety and effectiveness of standard of care treatments for CHE. Data collected through the registry may be used to address a range of research questions and use cases, including but not limited to: characterizing the natural history of the disease, evaluating the effectiveness and safety of commercially available medications for the treatment of CHE, providing information to support ongoing risk-benefit evaluation by drug manufacturers and regulators, and research related to drug utilization, disease burden, and unmet needs. Further, data collected will inform clinical decision making by patients and treating providers.
Study Type
OBSERVATIONAL
Enrollment
2,000
This is an observational (non-interventional) registry
CHE Disease Epidemiology and presentation
The major clinical outcome include an assessment of the epidemiology of CHE Disease; to better understand the presentation and natural history.
Time frame: Every 6 months for 10 years
CHE Disease management, and outcomes
The major clinical outcome include an assessment of the epidemiology of CHE Disease; to better understand the management and outcomes.
Time frame: Every 6 months for 10 years
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