Evaluation of Fecal Multi-target Biomarkers in the Screening of Digestive Tract Cancers

Inclusion Criteria: 1. Participants must be at least 18 years of age at the time of enrollment; 2. Participants must be scheduled to undergo gastroscopy and colonoscopy; 3. Participants must agree to undergo a two-year follow-up as outlined in the protocol; 4. Participants must be willing to participate and sign an informed consent form. Exclusion Criteria: 1. Have undergone gastrointestinal endoscopy screening within the past year; 2. History of any type of gastrointestinal malignancy; 3. Concurrent severe medical conditions that reduce the benefits of screening, such as severe pulmonary disease, kidney disease, liver disease, cardiovascular and cerebrovascular diseases, and hematological disorders; 4. Other situations where a physician determines that endoscopic screening poses excessive risk (e.g., hemodynamic instability) or offers no benefit (e.g., short life expectancy); 5. Pregnant or breastfeeding women.