Early Screening of Chronic Post-sternotomy Pain Using the DN4-i Questionnaire

N/ANot Yet RecruitingNCT07603271

Institute Arnault Tzanck, France120 enrolled

Overview

Chronic post-sternotomy pain (CPSP) is a common complication after cardiac surgery, with a reported prevalence between 30% and 50%. Several studies show that a significant proportion of patients experience persistent pain long after cardiac surgery, often with a neuropathic component. Internal mammary artery harvesting is known to cause intercostal nerve injury. Recent data suggest that early neuropathic pain, assessed using the DN4 score, may predict the chronicization of postoperative pain. This study is a prospective observationnal study to evaluate the association between early neuropathic pain (DN4-i ≥ 3/7 on postoperative day 5) and the occurrence of chronic post-sternotomy pain at 3 months in patients who underwent median sternotomy for coronary artery bypass grafting with internal mammary artery harvesting

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Chronic Pain, Postoperative Sternotomy Pain

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 years * Scheduled cardiac surgery with coronary artery bypass via median sternotomy with internal mammary artery harvesting * Patients receive an information sheet and a non-opposition form. Exclusion Criteria: * History of sternotomy * Early reoperation \< 30 days * Chronic treatment with strong opioids or neuropahtic pain medications * Severe cognitive impairment * Patients under legal protection or guardianship

Locations (1)

Outcomes

Primary Outcomes

Neuropathic Pain Questionnaire Interview (DN4i)

Abbreviated DN4i questionnaire Minimal : 0 Maximal : 7 The DN4i is a validated interview-based questionnaire designed to identify neuropathic pain. It consists of 7 sensory descriptors reported by the patient. A score ≥ 3/7 suggests the presence of neuropathic pain.

Time frame: Day 5

Secondary Outcomes

Numeric Rating Scale (NRS)

Pain intensity was assessed using an 11-point Numeric Rating Scale (0 = no pain, 10 = worst imaginable pain).

Time frame: 3 and 6 months

Neuropathic Pain Questionnaire Interview (DN4i)

Time frame: 3 and 6 month

5-level EQ-5D (EQ-5D-5L)

Evaluation of functionnal impact on quality of life with EQ-5D-5L The digits for the five dimensions can be combined into a 5-digit number that describes the patient's health state. Five items representing five dimensions: Mobility; Self-care; Usual activities; Pain and discomfort; Anxiety and depression. Responses are recorded on 5-point scales (1: no problems; 2: slight problems; 3: moderate problems; 4: severe problems; 5: extreme problems or complete inability).

Time frame: 3 months and 6 months