Local data regarding the effectiveness and safety of mannitol has been scarce. Therefore, the current study was planned, aiming to compare the change in mean anterior chamber depth and intraocular pressure (IOP) and to determine the frequencies of perioperative complications during cataract surgery in groups receiving mannitol versus placebo.
The literature shows that the effectiveness of mannitol in decreasing intraocular pressure (IOP) varies widely. Although it rapidly lowers IOP in the majority of people, clinical results and the extent of the reduction differ depending on a number of factors. Mannitol can be detrimental for patients with pulmonary edema or severe heart failure (congestive heart failure) because it quickly draws fluid into the bloodstream, increasing intravascular volume. In addition to contributing to the local literature, the results of this study will aid in determining the true efficacy and safety of mannitol.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Pakistan Air Force (PAF) hospital
Islamabad, Punjab Province, Pakistan
Change in the intraocular pressure
The change in the intraocular pressure, measured in mmHg, was noted at post-intervention and compared to the baseline.
Time frame: 45 minutes
Change in the anterior chamber depth
The change in the anterior chamber depth, measured in mm, was noted at post-intervention and compared to the baseline.
Time frame: 45 minutes
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