When patients undergo major surgery, they are connected to a ventilator during anesthesia. A heat and moisture exchange filter (HME filter) is routinely placed in the ventilator tubing to ensure that the inhaled air is warm and humidified. Today, HME filters are used routinely in all ventilator treatments. They are typically replaced once a day and discarded as regular waste after use. The purpose of this study is to investigate whether HME filters contain proteins and small biological particles from the patient's exhaled air.
Study Type
OBSERVATIONAL
Enrollment
10
Aalborg University Hospital
Gistrup, Denmark
RECRUITINGTotal endogenous protein amount captured in HME filters measured by standard biochemical assays.
Quantification of the total amount of endogenous proteins recovered from heat moisture exchange (HME) filters using Biuret based analysis.
Time frame: Through study completion, an average of 3 months.
Protein molecular weight and isoelectric point distribution in proteins captured by HME filters.
Distribution and representation of captured proteins according to molecular weight and isoelectric point characteristics determined by proteomic analysis.
Time frame: Through study completion, an average of 3 months.
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