The purpose of this study is to test the efficacy and safety of orforglipron in participants with T2D (type 2 diabetes) who participate in fasting during Ramadan. For each participant, the study will last up to 48 weeks with a minimum of 7 in clinic visits and 4 virtual visits.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
130
Administered orally
Sarojini Naidu Medical College
Agra, India
Osmania General Hospital
Hyderabad, India
Brij Medical Centre Pvt. Ltd.
Kanpur, India
Apollo Multispeciality Hospitals limited
Kolkata, India
KGN Diabetes and Endocrinology Centre
Mumbai, India
Mysore Medical College and Research Institute
Change from Baseline in Hemoglobin A1C (HbA1c)
Time frame: Baseline, up to 8 Weeks after Start of Ramadan
Percentage of Participants with an HbA1c of less than (<) 7 Percent (%) (53 millimeters per mole (mmol/mol))
Time frame: Baseline, Up to 8 Weeks after Start of Ramadan
Change From Baseline in Fasting Serum Glucose (FSG)
Time frame: Baseline, Up to 8 Weeks after Start of Ramadan
Percent Change from Baseline in Body Weight
Time frame: Baseline, Up to 8 Weeks after Start of Ramadan
Change in EuroQol 5-Dimension 5-Level (EQ-5D-5L) Index
Time frame: Baseline, Up to 8 Weeks after Start of Ramadan
Percent Change in HbA1c
Time frame: 4 Weeks Prior to Ramadan, Up to Week 8 after Start of Ramadan]
Percent Change in Body Weight
Time frame: 4 Weeks Prior to Ramadan, Up to Week 8 after Start of Ramadan]
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
CONTACT
Physicians interested in becoming principal investigators please contact
CONTACT
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Mysore, India
Supe Heart & Diabetes Hospital & Research Centre
Nashik, India
Diabetes Clinic
Nellore, India
Visakha Institute of Medical Sciences
Visakhapatna, India
King Abdulaziz University for Health Sciences Ministry of National Guard Health Affairs
Al-Ahsa, Saudi Arabia
...and 27 more locations