This prospective randomized clinical trial evaluates the duration of sensory blockade in patients undergoing shoulder surgery receiving interscalene brachial plexus blocks with either liposomal bupivacaine alone or liposomal bupivacaine combined with dexamethasone.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
80
Administration of an interscalene brachial plexus nerve block using 10 mL liposomal bupivacaine (133 mg) and 20 mL of 0.5% bupivacaine for postoperative analgesia following shoulder surgery.
6 mg preservative-free dexamethasone
time until resolution of sensory block
Patients will be called daily until resolution of their sensory block
Time frame: 0-10 days
duration of motor blockade
Time frame: 2, 12, 24, 36, 48, 72, and 96 hours postoperatively
pain scores (scale of 0-10)
Numeric Pain Rating Scale (NPRS): A score of 0 means "no pain," and 10 means "the worst pain imaginable
Time frame: 2, 12, 24, 36, 48, 72, and 96 hours postoperatively
opioid consumption (in oral morphine equivalents)
Time frame: 2, 12, 24, 36, 48, 72, and 96 hours postoperatively
known side effects of interscalene blocks
Time frame: 2, 12, 24, 36, 48, 72, and 96 hours postoperatively
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