Morpho-functional Evaluation of the Retina and Choroid Using Multimodal Imaging in Healthy Subjects and Patients With Retino-choroidal Diseases

N/ANot Yet RecruitingNCT07615699

Fondazione G.B. Bietti, IRCCS125 enrolled

Overview

The purpose of this prospective, longitudinal, single-center observational study is to identify, describe, and measure the morpho-functional characteristics and modifications of the retina and choroid using advanced multimodal imaging techniques. The study will evaluate patients affected by retino-choroidal diseases and compare them with healthy controls over a 5-year follow-up period to track the evolution of these parameters over time.

Study Type

OBSERVATIONAL

Enrollment

125

Conditions

Retinal Diseases Choroidal Diseases Healthy Subjects

Eligibility

Sex: ALLMin age: 6 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * freely given informed consent acquired prior to the start of the study. * Participant's capacity to understand the informed consent and study procedures. * Age ≥ 6 years (with parental/guardian consent for minors). * Patients affected by any retino-choroidal disease. * Healthy subjects showing no retino-choroidal pathology. Exclusion Criteria: * Patient unable and/or unwilling to cooperate. * Presence of media opacities (dioptric media) that prevent image acquisition or significantly reduce the quality of the obtained images.

Outcomes

Change from baseline in retinal thickness measured by OCT

Change in retinal thickness from baseline to each follow-up visit, measured by optical coherence tomography (OCT). Retinal thickness will be reported in micrometers (µm), including central macular thickness and/or retinal layer thicknesses, as applicable.