Effect of Miralax NPO Time on Residual Gastric Volumes and Bowel Preparation

N/ANot Yet RecruitingNCT07616908

Stanford University200 enrolled

Overview

The goal of this clinical trial is to assess differences in residual gastric volumes after stopping Miralax ingestion at different time points (1-4 hours) prior to anesthesia induction.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

200

Conditions

Residual Gastric Contents Polyethylene Glycol

Interventions

Stopping Miralax ingestion 4 hours prior to anesthesia inductionBEHAVIORAL

Stopping Miralax ingestion 4 hours prior to anesthesia induction

Stopping Miralax ingestion 3 hours prior to anesthesia inductionBEHAVIORAL

Stopping Miralax ingestion 3 hours prior to anesthesia induction

Stopping Miralax ingestion 2 hours prior to anesthesia inductionBEHAVIORAL

Stopping Miralax ingestion 2 hours prior to anesthesia induction

Eligibility

Sex: ALLMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing both EGD and colonoscopy * Use of Miralax for cleanout * Patients \<19 years old Exclusion Criteria: * Patients with a history of delayed gastric emptying (eg diabetic, GLP-1 intake) * Patients with a history of gastric sleeve surgery * Use of Golytely for cleanout * Emergent EGD/colonoscopies * EGD/colonoscopies for foreign body removal and/or decompression * Known neurologic compromise * Presence of pre-existing ostomy, short bowel syndrome, gastric retention, intestinal obstruction, ileus, bowel perforation, toxic colitis, toxic megacolon, swallowing difficulties * Pre-existing electrolyte derangements * Allergy to Miralax

Outcomes

Primary Outcomes

Residual gastric volume as measured by EGD

Time frame: To be performed at the start of the EGD immediately after anesthesia induction.

Secondary Outcomes

Preoperative gastric POCUS volume assessment

Time frame: Performed prior to anesthesia induction

Effectiveness of colonoscopy cleanout

The effectiveness of colonoscopy cleanout will be assessed by the Boston Bowel Preparation Scale (BBPS).

Time frame: Performed during the colonoscopy portion following upper GI endoscopy (EGD)

Incidence of aspiration on induction and perioperative aspiration

Time frame: On anesthesia induction

Data from ClinicalTrials.gov

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