Effect of Miralax NPO Time on Residual Gastric Volumes and Bowel Preparation

N/ANot Yet RecruitingNCT07616908

Stanford University200 enrolled

Overview

The goal of this clinical trial is to assess differences in residual gastric volumes after stopping Miralax ingestion at different time points (2, 4, 6 hours) prior to anesthesia induction and compare it to the control (current institutional standard of care where no Miralax is given on the day of surgery).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

200

Conditions

Residual Gastric Contents Polyethylene Glycol

Interventions

Stopping Miralax ingestion 4 hours prior to anesthesia inductionBEHAVIORAL

Stopping Miralax ingestion 4 hours prior to anesthesia induction

Stopping Miralax ingestion 6 hours prior to anesthesia inductionBEHAVIORAL

Stopping Miralax ingestion 6 hours prior to anesthesia induction

Stopping Miralax ingestion 2 hours prior to anesthesia inductionBEHAVIORAL

Stopping Miralax ingestion 2 hours prior to anesthesia induction

Eligibility

Sex: ALLMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing both EGD and colonoscopy * Use of Miralax for cleanout * Patients \<19 years old Exclusion Criteria: * Patients with a history of delayed gastric emptying (eg diabetic, GLP-1 intake) * Patients with a history of gastric sleeve surgery * Use of Golytely for cleanout * Emergent EGD/colonoscopies * EGD/colonoscopies for foreign body removal and/or decompression * Known neurologic compromise * Presence of pre-existing ostomy, short bowel syndrome, gastric retention, intestinal obstruction, ileus, bowel perforation, toxic colitis, toxic megacolon, swallowing difficulties * Pre-existing electrolyte derangements * Allergy to Miralax

Outcomes

Primary Outcomes

Residual gastric volume as measured by EGD

Time frame: To be performed at the start of the EGD immediately after anesthesia induction.

Secondary Outcomes

Preoperative gastric POCUS volume assessment

Time frame: Performed prior to anesthesia induction

Effectiveness of colonoscopy cleanout

The effectiveness of colonoscopy cleanout will be assessed by the Boston Bowel Preparation Scale (BBPS).

Time frame: Performed during the colonoscopy portion following upper GI endoscopy (EGD)

Incidence of aspiration on induction and perioperative aspiration

Time frame: On anesthesia induction

Data from ClinicalTrials.gov

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