Diagnostic Accuracy of Eus Fnb in Difficult to Reach Lesions

Fondazione Policlinico Universitario Agostino Gemelli IRCCS131 enrolled

Overview

The present study aims at comprehensively assessing the diagnostic performance and safety profile of EUS-FNB as a primary diagnostic tool for suspected malignancies in anatomically complex or deeply situated regions, including the duodeno-jejunal, and hepatic hilar areas. By focusing on lesions that are challenging to reach due to their intricate anatomy or profound depth, investigators seek to provide valuable insights into the potential role of EUS-FNB in enhancing diagnostic accuracy and safety in these complex clinical scenarios.

Study Type

OBSERVATIONAL

Enrollment

131

Conditions

Hilar Cholangiocarcinoma Duodenal Neoplasms

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. age ≥ 18 years; 2. patients with one or multiple lesions adjacent to the distal duodenum, or the proximal jejunum, or the hepatic hilum that underwent EUS in our Institution over the past 10 years; 3. Patients monitored for at least 6 months after EUS-FNB or until death (follow-up less than 6 months); 4. Available data; 5. Written informed consent. Exclusion Criteria: 1. Age less than 18 years old; 2. Patient unable to sign the informed consent.

Locations (1)

Outcomes

Primary Outcomes

Diagnostic accuracy of eus fnb

Diagnostic accuracy, calculated according to the formula = (true positives + true negatives) / (true positives + false positives + true negatives + false negatives), of EUS-FNB for all the difficult-to-detect abdominal lesions.

Time frame: At 6 months after EUS-FNB, or at the time of surgical histopathologic diagnosis if surgery occurred earlier