This trial is a multicenter randomized, double-blind, placebo-controlled phase III study to evaluate the efficacy and safety of Bempedoic Acid Tablets in patients with hyperlipidemia not adequately controlled by Statins.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
222
bempedoic acid 180 mg tablet taken orally, once daily. Participants in the experiment remain on ongoing lipid-modifying therapy
Matching placebo tablet taken orally, once daily. Participants in the experiment remain on ongoing lipid-modifying therapy
Percentage change from baseline in LDL-C levels at Week 12
Time frame: Baseline, Week 12
Proportion of participants achieving LDL-C target
Time frame: Baseline, Week 12
Percentage change from baseline in non-HDL-C、ApoB、TC、hs-CRP levels at Week 12
Time frame: Baseline, Week 12
Adverse events (AEs) and serious adverse events (SAEs) during the study
Time frame: Baseline, Week 13
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