This study compares the efficacy of a 5-day post-operative oral prednisone regimen (40 mg daily) with the standard intraoperative steroid regimen, focusing on pain, swelling, range of motion, opioid use, and glucose levels monitored continuously.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
104
40 mg daily for 5 days
Provides real-time glucose readings for up to 14 days
Temporary medical-grade tattoos that provide real-time monitoring of knee swelling and range of motion
Columbia University Irving Medical Center
New York, New York, United States
Pain at Rest
Pain intensity at rest will be measured using the 11-point Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst imaginable pain). The NRS is a validated and standardized tool for assessing patient-reported pain.
Time frame: 2 weeks
Pain with Ambulation
Pain intensity with ambulation will be measured using the 11-point Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst imaginable pain). The NRS is a validated and standardized tool for assessing patient-reported pain.
Time frame: 2 weeks
Swelling
Knee joint circumference will be measured in centimeters at the joint line.
Time frame: 2 weeks
Range of Motion
Time frame: 2 weeks
Opioid Consumption
Time frame: 2 weeks
Continuous Glucose Levels
Time frame: 2 weeks
Adverse Outcomes
Total number of adverse events related to steroid treatment will be recorded.
Time frame: 2 weeks
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