End-Tidal CO2 (ETCO2) Trends in Out-of-Hospital Cardiac Arrest

N/AActive Not RecruitingNCT07632430

Office of the Medical Director for EMS in Oklahoma City and Tulsa3,500 enrolled

Overview

The investigators aim to assess the relationship between patient characteristics, prehospital treatments, and vital signs to determine if a threshold EtCO2 value, a change in EtCO2 value (final - initial), or a trend in EtCO2 (positive/negative) is a better predictor of patient survival to discharge. The secondary aim of this project is to identify significant predictors of neurologically intact patient survival as indicated by a cerebral performance category (CPC) score of 1-2.

Study Type

OBSERVATIONAL

Enrollment

3,500

Conditions

Prehospital Resuscitation End-Tidal Carbon Dioxide Cardiac Arrest, Out-Of-Hospital Prehospital Emergency Medical Services

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria * EHR's resulting from 9-1-1 response * Adult patients (aged 18+ at time of cardiac event) * experiencing out-of-hospital cardiac arrest (OHCA) * transported by an agency under OMD oversight * must have at least 2 EtCO2 values captured during care Exclusion Criteria * EHR's resulting from inter-facility scheduled or unscheduled medical transfers * pediatric patients (those aged \<18 at time of incident) or unknown age * ROSC obtained prior to arrival of EMS * insufficient vital sign data

Outcomes

Primary Outcomes

Survival to Hospital Discharge

lack of terminiation of CPR during prehospital or in hospital care

Time frame: 90 days

Secondary Outcomes

Neurologically Intact Patient Survival

Based on Gasgow-Pittsburgh Cerebral Performance Category (CPC) score which ranges from 1 (best) to 5 (worst). Neurologically intact is defined as a score of 1-2 among survivors