The goal of this randomized controlled trial was to learn whether a combined aerobic and resistance exercise program could improve physical function and muscle health in people receiving peritoneal dialysis. Researchers compared an exercise group with a control group to evaluate the effects of regular exercise. The main questions the study aimed to answer were: * Can regular exercise improve physical performance and muscle strength in people receiving peritoneal dialysis? * Can regular exercise improve body composition and blood markers related to muscle health? Before the exercise program, participants completed a one-month training period to learn the exercises and practice them safely. Participants in the exercise group: * Performed combined aerobic and resistance exercises for 8 weeks * Completed assessments before and after the exercise program Participants in the control group: * Continued their usual care * Completed assessments before and after the study period
People receiving peritoneal dialysis often experience reduced physical function, muscle weakness, and changes in body composition. This randomized controlled trial evaluated the effects of a combined aerobic and resistance exercise program in adults receiving peritoneal dialysis. Before the intervention, participants completed a one-month training and adaptation period to learn the exercises and ensure safe participation. Participants were then assigned to either an exercise group or a control group. The exercise group performed a structured combined aerobic and resistance exercise program for 8 weeks, while the control group continued usual care. Researchers evaluated physical performance, muscle strength, body composition, and blood markers related to muscle health before and after the intervention period. The study aimed to determine whether regular exercise could improve physical function and muscle health in people receiving peritoneal dialysis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
36
Participants performed a structured combined aerobic and resistance exercise program for 8 weeks. Before the intervention period, participants completed a one-month training and adaptation phase to learn the exercises and ensure safe participation. The exercise program aimed to improve physical performance, muscle strength, and muscle health in people receiving peritoneal dialysis.
Mugla Sitki Kocman University Faculty of Medicine, Mugla Training and Research Hospital
Muğla, Muğla, Turkey (Türkiye)
Physical Performance
Changes in physical performance assessed using the 6-minute walk test after 8 weeks of combined aerobic and resistance exercise.
Time frame: Baseline and after 8 weeks of intervention
Changes in right handgrip strength
Changes in right handgrip strength measured in kilograms after 8 weeks of combined aerobic and resistance exercise.
Time frame: Baseline and after 8 weeks of intervention
Changes in left handgrip strength
Changes in left handgrip strength measured in kilograms after 8 weeks of combined aerobic and resistance exercise.
Time frame: Baseline and after 8 weeks of intervention
Changes in leg strength
Changes in lower extremity muscle strength measured using a leg and back dynamometer after 8 weeks of combined aerobic and resistance exercise.
Time frame: Baseline and after 8 weeks of intervention
Changes in flexibility
Changes in flexibility assessed using the Modified Back-Saver Sit-and-Reach Test after 8 weeks of combined aerobic and resistance exercise.
Time frame: Baseline and after 8 weeks of intervention
Changes in Fat Tissue Index (FTI)
Changes in Fat Tissue Index measured by by bioimpedance spectroscopy after 8 weeks of combined aerobic and resistance exercise.
Time frame: Baseline and after 8 weeks of intervention
Changes in Lean Tissue Index (LTI)
Changes in Lean Tissue Index measured by by bioimpedance spectroscopy after 8 weeks of combined aerobic and resistance exercise.
Time frame: Baseline and after 8 weeks of intervention
Changes in serum IGF-1 levels
Changes in serum insulin-like growth factor-1 (IGF-1) levels after 8 weeks of combined aerobic and resistance exercise.
Time frame: Baseline and after 8 weeks of intervention
Changes in serum ACTH levels
Changes in serum adrenocorticotropic hormone (ACTH) levels after 8 weeks of combined aerobic and resistance exercise.
Time frame: Baseline and after 8 weeks of intervention
Changes in serum myostatin levels
Changes in serum myostatin levels after 8 weeks of combined aerobic and resistance exercise.
Time frame: Baseline and after 8 weeks of intervention
Changes in serum irisin levels
Changes in serum irisin levels after 8 weeks of combined aerobic and resistance exercise.
Time frame: Baseline and after 8 weeks of intervention
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