This study will evaluate whether a nutritional intervention is better than another to reduce the incidence of overt hepatic encephalopathy in patients undergoing TIPS insertion for refractory ascites.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
50
As participants are blinded, description of the intervention is meant to maintain the blinding. Participants will meet the study dietitian who will perform a nutritional assessment. The study dietitian will then prescribe a high-energy and high-protein diet with or without the use of oral nutritional supplements that will fit your taste preferences and dietary needs. The nutritional intervention will focus on having 3 meals per day and 3 snacks per day, including at bedtime.
As participants are blinded, description of the intervention is meant to maintain the blinding. Participants will meet the study dietitian who will perform a nutritional assessment. The study dietitian will then prescribe a high-energy and high-protein diet with or without the use of oral nutritional supplements that will fit your taste preferences and dietary needs. The nutritional intervention will focus on having 3 meals per day and 3 snacks per day, including at bedtime.
McGill University Health Centre
Montreal, Quebec, Canada
Incidence of overt hepatic encephalopathy
Time frame: 6 months
Changes in nutritional status using the PG-SGA scale
Time frame: 6 months
Changes in brain function using the Stroop Test (EncephalApp)
Time frame: 6 months
Changes in frailty using the Liver Frailty Index
Time frame: 6 months
Changes in patient-reported outcomes using Chronic Liver Disease Questionnaire
Time frame: 6 months
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