This study evaluates corneal epithelial thickness using anterior segment optical coherence tomography (AS-OCT) in patients with refractive errors. It aims to assess the relationship between epithelial thickness patterns and different types of refractive errors.
Refractive errors are among the most common ocular conditions affecting visual acuity. Corneal epithelial thickness has been suggested to play a role in the optical properties of the eye and may vary among different refractive states. This observational study aims to evaluate corneal epithelial thickness mapping using anterior segment optical coherence tomography (AS-OCT) in patients with refractive errors. Patients will be assessed and categorized according to their refractive status, and epithelial thickness measurements will be obtained and analyzed. The study seeks to investigate potential correlations between epithelial thickness distribution and different types of refractive errors to enhance understanding of corneal biomechanics in refractive conditions.
Study Type
OBSERVATIONAL
Enrollment
360
Sohag University Hospital
Sohag, Sohag Governorate, Egypt
Measurement of corneal epithelial thickness using AS-OCT
Corneal epithelial thickness will be measured using anterior segment optical coherence tomography (AS-OCT). Measurements will include central and regional epithelial thickness values in microns in patients with different refractive errors.
Time frame: At baseline during a single study visit when participants undergo AS-OCT examination.
Comparison of epithelial thickness between myopic and hyperopic eyes
Corneal epithelial thickness will be compared between myopic and hyperopic eyes using AS-OCT measurements.
Time frame: At baseline (single visit)
Comparison of epithelial thickness in eyes with and without astigmatism
Corneal epithelial thickness will be evaluated and compared between eyes with astigmatism and those without astigmatism using AS-OCT.
Time frame: At baseline (single visit)
Corneal epithelial thickness asymmetry across corneal regions and inter-eye comparison
Epithelial thickness will be assessed across different corneal regions and compared between both eyes to evaluate inter-eye asymmetry.
Time frame: At baseline (single visit)
Comparison of epithelial thickness in low and high refractive errors
Corneal epithelial thickness profiles will be compared between low and high degrees of myopia and hyperopia using AS-OCT measurements.
Time frame: At baseline (single visit)
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