This study aims to evaluate the clinical, psychological, and functional outcomes of adolescents with anorexia nervosa receiving multidisciplinary care in hospital settings. Participants are treated either in a day hospitalization program or in a full-time inpatient program, in accordance with the French national guidelines (Haute Autorité de Santé, HAS) for the management of anorexia nervosa. The study seeks to better understand the evolution of patients' health status over time, including nutritional, psychological, and social dimensions, and to identify factors associated with treatment response. Data will be collected as part of routine clinical care without modification of the standard therapeutic management. The results of this study may help improve clinical practices and optimize care pathways for adolescents with anorexia nervosa.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
307
Participants admitted to the day hospital receive a multidisciplinary treatment program including psychiatric, medical, nutritional, and psychosocial care, delivered through structured daytime sessions without overnight stay.
Participants not admitted to the day hospital program receive usual care according to standard clinical pathways outside the specialized day hospital setting.
Change in Body Mass Index (BMI)
Time frame: From admission request to at least 18 months follow-up
Change in eating disorder psychopathology assessed by EDE-Q
Eating disorder psychopathology will be assessed using the Eating Disorder Examination Questionnaire (EDE-Q), a self-report scale ranging from 0 to 6, with higher scores indicating more severe symptoms. The assessment will be performed at admission and discharge.
Time frame: Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission
Change in body image concerns assessed by BSQ
Body image concerns will be assessed using the Body Shape Questionnaire (BSQ), a self-report scale with higher scores indicating greater body dissatisfaction. The assessment will be performed at admission and discharge.
Time frame: Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission
Change in anxiety and depression symptoms assessed by HADS
Anxiety and depression symptoms will be assessed using the Hospital Anxiety and Depression Scale (HADS), which includes subscales for anxiety and depression, each ranging from 0 to 21, with higher scores indicating greater symptom severity. The assessment will be performed at admission and discharge.
Time frame: Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission
Change in obsessive-compulsive symptoms assessed by MOCI
Obsessive-compulsive symptoms will be assessed using the Maudsley Obsessive-Compulsive Inventory (MOCI), where higher scores indicate more severe symptoms. The assessment will be performed at admission and discharge.
Time frame: Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission
Change in eating disorder-related quality of life assessed by EDQoL
Quality of life related to eating disorders will be assessed using the Eating Disorders Quality of Life (EDQoL) questionnaire, with higher scores indicating greater impairment. The assessment will be performed at admission and discharge
Time frame: Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission
Change in autistic traits assessed by AQ-10
Autistic traits will be assessed using the Autism Spectrum Quotient (AQ-10), a brief screening tool with higher scores indicating more pronounced autistic traits. The assessment will be performed at admission and discharge
Time frame: Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission
Change in family functioning assessed by FAD-12
Family functioning will be assessed using the Family Assessment Device (FAD-12), with higher scores indicating poorer family functioning. The assessment will be performed at admission and discharge.
Time frame: Baseline (at admission), discharge (end of hospitalization), and follow-up at least 18 months after admission
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