This clinical study will enroll 100 participants from the 2-month-old (minimum 6 weeks) group who previously participated in the Phase III clinical trial of the 13-valent pneumococcal polysaccharide conjugate vaccine (CRM197, TT vector) (Protocol No.: CS-CTP-PCV), with 50 participants in each of the treatment and control groups, and who have completed blood sample collection for the 1-year and 2-year immunogenicity studies. All participants will have 3.0-3.5 mL of venous blood collected for the immunogenicity study.
Study Type
OBSERVATIONAL
Enrollment
100
3.0 to 3.5 mL of venous blood will be collected for the immunodynamic study.
3.0 to 3.5 mL of venous blood will be collected for the immunodynamic study.
Seropositivity rate for serotype-specific pneumococcal IgG antibodies (antibody concentration ≥ 0.35 μg/ml) among trial participants
Time frame: 4 years after completion of the full vaccination series
Geometric mean concentration (GMC) of antibodies among trial participants
Time frame: 4 years after completion of the full vaccination series
Proportion of trial participants with serum-type-specific pneumococcal IgG antibody among trial participants
Time frame: 4 years after completion of the full vaccination series
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