Metabolic and Clinical Effects of Hyperchloremia During HoLEP Surgery.

N/ANot Yet RecruitingNCT07655830

Ankara City Hospital Bilkent45 enrolled

Overview

This study aims to evaluate the changes between preoperative and postoperative serum chloride levels in patients undergoing HoLEP surgery and to investigate the metabolic and clinical effects of this change. The study is observational, and no additional interventions will be performed.

Although isotonic irrigation fluids used in HoLEP surgery reduce the risk of hyponatremia associated with TUR syndrome, high-volume fluid absorption may lead to hyperchloremia and subsequent metabolic acidosis. This prospective, observational, single-center study, conducted at Ankara Bilkent City Hospital, aims to identify early markers of this condition to optimize perioperative management.

Study Type

OBSERVATIONAL

Enrollment

Conditions

HoLEP (Holmium Laser Enucleation of Prostate)Hyperchloremia Perioperative Management

Interventions

HoLEP surgeryPROCEDURE

All parameters are part of routine clinical practice; no additional examinations are required

Eligibility

Sex: MALEMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients scheduled for elective HoLEP surgery. * Patients providing written informed consent Exclusion Criteria: * Preoperative metabolic acidosis. * Advanced renal failure. * Emergency surgery. * Missing data.

Outcomes

Primary Outcomes

Change in serum chloride level

Time frame: Perioperative

Secondary Outcomes

irrigation volume

Time frame: Perioperative

Arter blood gas

Time frame: Perioperative

Data from ClinicalTrials.gov

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