Gingival recession is a common mucogingival deformity that may result in root hypersensitivity, esthetic concern, plaque accumulation, and difficulty in oral hygiene maintenance. Modified coronally advanced flap procedures are widely used for Cairo RT1 gingival recession defects. Platelet-rich fibrin has been used as an autologous biologic adjunct, while hyaluronic acid has shown potential benefits in wound hydration, inflammation modulation, and soft tissue healing. Aim: To evaluate the clinical effectiveness of multilayered platelet-rich fibrin with cross-linked hyaluronic acid compared with platelet-rich fibrin alone in the treatment of Cairo RT1 gingival recession defects using modified coronally advanced flap without vertical releasing incisions.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
30
root coverage with multilayered PRF
root coverage with multilayered PRF and hyaluronic acid application
Gulf Medical University
Ajman, Ajman Emirate, United Arab Emirates
Percentage of root coverage
Time frame: baseline, 3 months, 6 months
postoperative pain VAS score 1-10
VAS score 1-10
Time frame: baseline, 3 days, 3 weeks
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