Evaluation of OMEGA-3 Effect in Alveolar Socket Preservation in Aesthetic Zone

Cairo University10 enrolled

Overview

To evaluate the effect of Omega-3 in preserving bone after extraction

The evaluation of the effect of omega-3 on the bone of the socket with changes in the dimensions like vertical and horizontal bone changes 3months after extraction .

Study Type

INTERVENTIONAL

Allocation

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Omega-3 Fatty Acids Socket Preservation Esthetic Zone

Interventions

Omega 3 Fish Oil supplementsDIETARY_SUPPLEMENT

omega-3 fatty acid supplement

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients with non-restorable remaining roots. 2. Patients free of systemic conditions that might affect the surgical procedure or the quantity or quality of bone (uncontrolled hypertension, uncontrolled diabetes). Exclusion Criteria: 1. Patients below 18 years old 2. Patients with hypersensitivity to omega-3, drug formulations or allergic to seafood. 3. Pregnant or lactating females 4. Patients undergoing chemotherapy or radiotherapy 5. Smokers

Locations (1)

Faculty of Dentistry

Cairo, Egypt

Outcomes

Primary Outcomes

Post-operative pain

Visual Analogue Scale score "VAS score" From 0-10 scores score 0 is no pain which is the best 1-4 is mild pain 5 is moderate pain from 5 -10 pain is getting worse and 10 is the worst

Time frame: immediately after extraction and the second day after extraction

Secondary Outcomes

Radiographic bone changes "horizontal bone changes " using Cone beam CBCT

Performing one CBCT before extraction and one new CBCT after 3 months of extraction and omega-3 placement then comparing both CBCTs by J image computer program to get the difference in vertical bone measurements in millimeter

Time frame: before extraction and 3months after omega 3 placement

Radiographic bone changes " Vertical bone fill" using CBCT

Time frame: before and after 3 months of extraction and omega-3 placement

Radiographic bone changes "Bone density" using CBCT

Performing one CBCT before extraction and one new CBCT after 3 months of extraction and omega-3 placement then comparing both CBCTs by J image computer program to get the radiographic bone changes in millimeter and Hounsfield units

Time frame: 3 months after extraction and placement of omega-3

Histological examination

using Hematoxylin and Eosin staining to measure the area of newly formed bone "Percentage"

Time frame: after 3months of extraction during implant placement bone is taken using trephine bur

Healing Index "HI" by Landry et al using scores

Data from ClinicalTrials.gov

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