To conduct a multi-center, randomized, controlled clinical study aimed at formally evaluating the impact of different acupuncture methods on the success rate in patients with recurrent implantation failure
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
312
nonpenetrating placebo needles
indwelling intradermal needles
combining fire needle and regular acupuncture
Tongji Hospital,Tongji medical college,HUST
Wuhan, Hubei, China
clinical pregnancy
defined as ultrasonographic detection of an intrauterine gestational sac following embryo transfer
Time frame: 2 years
β-hCG-positive pregnancy
defined as serum β-hCG concentration \>10 mIU/mL on day 14 post-transfer
Time frame: 2 years
live birth
defined as the delivery of 1 or more living infants at greater than 20 weeks' gestation or birth weight of at least 400 g
Time frame: 3 years
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