The aim of this protocol is to assess physiological responses during various physical exercise protocols (whole-body exercise such as cycling or treadmill running, or localised exercise such as knee extension) and during inhalation of a gas mixtures with various oxygen contents (similar to exposure at high altitude).
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
305
Subjects will perform an exercise test while inhaling a hypoxic gas mixture
CReSI (centre de recherche en santé intégrée)
La Tronche, France
Muscle oxygenation
Measured by NIRS in % saturation
Time frame: During 5 minutes before starting the exercise test, continuously during the exercise test and during 10 minutes immediatly after the end of the exercise test
Gas exchange
Oxygen consumption and cardon dioxide production measured at the mouth, measured in ml/min
Time frame: During 5 minutes before starting the exercise test, continuously during the exercise test and during 10 minutes immediatly after the end of the exercise test
Heart rate
Measured by ECG in bpm
Time frame: During 5 minutes before starting the exercise test, continuously during the exercise test and during 10 minutes immediatly after the end of the exercise test
Limb blood flow
Measured by Doppler ultrasound in ml/min
Time frame: During 5 minutes before starting the exercise test, continuously during the exercise test and during 10 minutes immediatly after the end of the exercise test
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